Results The above-mentioned transdermal enhancers showed the significant effect on sinomenine in SG in vitro with the density sequence as Azone> mentha camphor> oleic acid, and 2% Azone plus 10% oleic acid had the strongest effect in all. 结果几种促透剂对青藤碱凝胶透皮速率均有明显作用,其促渗强度依次为氮酮>薄荷脑>油酸,其中以2%氮酮和10%油酸混合物的促透作用最强。